Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3603721 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL8701138 | 0.76 | KDM4E (0.32) | KDM4E | |
| SCHEMBL5231523 | 0.72 | PTPN1 (0.36) | KDM4E | |
| SCHEMBL26412450 | 0.72 | HTR2A (0.30) | — | |
| SCHEMBL6139350 | 0.71 | SMN1; SMN2 (0.40) | KDM4E | |
| SCHEMBL13604600 | 0.70 | PDCD1 (0.34) | KDM4EMAPK1 | |
| SCHEMBL320556 | 0.70 | RORC (0.39) | NOTUMKDM4EMAPK1 | |
| SCHEMBL6641986 | 0.69 | — | — | |
| SCHEMBL3255688 | 0.69 | RECQL (0.32) | MAPK1 | |
| SCHEMBL7698624 | 0.69 | TSHR (0.44) | KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322331-A2 | FATTY ACID SYNTHASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002009651-A2 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |