Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821681 | 0.86 | HDAC6 (0.49) | KMT2AALDH1A1CYP3A4LMNAMEN1 | |
| SCHEMBL28010037 | 0.86 | HDAC6 (0.49) | KMT2AALDH1A1CYP3A4LMNAMEN1 | |
| SCHEMBL27882319 | 0.85 | HDAC6 (0.47) | KMT2AALDH1A1CYP3A4LMNAMEN1 | |
| SCHEMBL27845616 | 0.83 | HDAC6 (0.46) | KMT2AALDH1A1CYP3A4LMNAMEN1 | |
| SCHEMBL28623032 | 0.81 | TSHR (0.49) | TSHRKMT2AALDH1A1CYP3A4LMNA | |
| SCHEMBL8592495 | 0.79 | KMT2A (0.43) | TSHRKMT2AALDH1A1CYP3A4MTNR1A | |
| SCHEMBL3939107 | 0.79 | ALDH1A1 (0.49) | TSHRKMT2AALDH1A1CYP3A4MTNR1A | |
| SCHEMBL7766565 | 0.78 | ALDH1A1 (0.53) | TSHRKMT2AALDH1A1LMNATP53 | |
| SCHEMBL28605734 | 0.75 | MAPT (0.49) | TSHRKMT2AALDH1A1LMNAMTNR1A | |
| SCHEMBL29217831 | 0.75 | DPP4 (0.41) | TSHRKMT2AALDH1A1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323596-A | Interleukin-17 inhibitors | 诺华股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-5705504-A | PLATELET ACTIVATING FACTOR | J. URIACH & CIA, S.A. (ES) | 1998-01-06 | — | — | US | disclosed |