SCHEMBL870124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL870125	1.00	NPC1 (0.45)	NPC1RAB9APDE4BGPR55CNR1
	SCHEMBL16104306	1.00	NPC1 (0.45)	NPC1RAB9APDE4BGPR55CNR1
	SCHEMBL870459	0.87	PDE4B (0.49)	NPC1RAB9APDE4BGPR55CNR1
	SCHEMBL870458	0.87	PDE4B (0.49)	NPC1RAB9APDE4BGPR55CNR1
	SCHEMBL8183839	0.87	PDE4B (0.49)	NPC1RAB9APDE4BGPR55CNR1
	SCHEMBL871175	0.87	PDE4B (0.46)	NPC1RAB9APDE4BGPR55CNR1
	SCHEMBL871176	0.87	PDE4B (0.46)	NPC1RAB9APDE4BGPR55CNR1
	Hydrochloric Acid SCHEMBL3700634	0.86	PDE4B (0.46)	NPC1RAB9APDE4BGPR55CNR1
	Hydrochloric Acid SCHEMBL3690679	0.86	PDE4B (0.46)	NPC1RAB9APDE4BGPR55CNR1
	SCHEMBL870152	0.86	PDE4B (0.41)	PDE4BCYP2C19PDE4DHTR3AABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.