SCHEMBL870152

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL870153	1.00	PDE4B (0.41)	PDE4BCYP3A4CYP2C9CYP2C19KCNH2
	SCHEMBL3011823	0.87	ABCB1 (0.39)	PDE4BABCB1MAP2K2MAP2K1TYK2
	SCHEMBL3011826	0.87	ABCB1 (0.39)	PDE4BABCB1MAP2K2MAP2K1TYK2
	SCHEMBL870526	0.86	PDE4B (0.45)	PDE4BCYP3A4CYP2C9CYP2C19KCNH2
	SCHEMBL870527	0.86	PDE4B (0.45)	PDE4BCYP3A4CYP2C9CYP2C19KCNH2
	SCHEMBL870124	0.86	NPC1 (0.45)	PDE4BCYP2C19ABCB1MAP2K2MAP2K1
	SCHEMBL16104306	0.86	NPC1 (0.45)	PDE4BCYP2C19ABCB1MAP2K2MAP2K1
	SCHEMBL870125	0.86	NPC1 (0.45)	PDE4BCYP2C19ABCB1MAP2K2MAP2K1
	SCHEMBL871893	0.83	MELK (0.37)	PDE4BABCB1MAP2K2MAP2K1TYK2
	SCHEMBL871894	0.83	MELK (0.37)	PDE4BABCB1MAP2K2MAP2K1TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.