Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477354 | 0.90 | ACE (0.51) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL11370729 | 0.90 | ACE (0.51) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL3277645 | 0.83 | ACE (0.59) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL3277639 | 0.83 | ACE (0.59) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL10477452 | 0.83 | ACE (0.47) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL10477455 | 0.83 | ACE (0.47) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL9502547 | 0.82 | ACE (0.64) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL16448191 | 0.82 | ACE (0.64) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL2890189 | 0.78 | ACE (0.53) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL10604860 | 0.78 | ACE (0.53) | ACEITGB3ITGA2BPTPN1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750499-A | ANTITUMOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-05-12 | — | — | US | disclosed |