Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.64 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.63 |
| ▸ | CTSS | P25774 | 6/20 | 0.57 |
| ▸ | CTSK | P43235 | 5/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 6/20 | 0.55 |
| ▸ | PPARG | P37231 | 5/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16448191 | 1.00 | ACE (0.64) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL7390262 | 0.89 | ACE (0.61) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL5374891 | 0.89 | ACE (0.61) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL1368753 | 0.89 | ACE (0.64) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL1458942 | 0.89 | PPARA (0.65) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL25284980 | 0.89 | ACE (0.64) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL231980 | 0.89 | CTSS (0.71) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL1310547 | 0.89 | CTSS (0.71) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL25672 | 0.89 | PPARA (0.65) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL5061931 | 0.89 | PPARA (0.65) | ACEITGB3ITGA2BCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538367-A1 | DERIVATIVES OF PITUITARY POSTERIOR LOBE HORMONES | Ferring AB (SE) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000996-A1 | DERIVATIVES OF PITUITARY POSTERIOR LOBE HORMONES | FERRING AB (SE) | 1992-01-23 | — | — | WO | disclosed |