Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 10/20 | 0.34 |
| ▸ | CA9 | Q16790 | 8/20 | 0.33 |
| ▸ | CA1 | P00915 | 7/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705734 | 0.96 | AOC2 (0.37) | AOC2PLK1MEN1PSMD14BLM | |
| SCHEMBL8700130 | 0.88 | AOC2 (0.39) | AOC2L3MBTL1 | |
| SCHEMBL8699333 | 0.86 | AOC2 (0.47) | AOC2MEN1BLMKMT2AL3MBTL1 | |
| SCHEMBL8704334 | 0.81 | AOC2 (0.43) | AOC2L3MBTL1LMNA | |
| SCHEMBL8183727 | 0.81 | AOC2 (0.43) | AOC2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8704321 | 0.80 | AOC2 (0.42) | AOC2MEN1KMT2AL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL8704455 | 0.80 | AOC2 (0.42) | AOC2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8707259 | 0.78 | AOC2 (0.41) | AOC2PLK1MEN1BLMKMT2A | |
| SCHEMBL8703315 | 0.78 | AOC2 (0.36) | AOC2PSMD14L3MBTL1LMNA | |
| SCHEMBL8707029 | 0.78 | AOC2 (0.39) | AOC2MEN1BLMKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |