Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.48 |
| ▸ | DRD2 | P14416 | 15/20 | 0.41 |
| ▸ | DRD3 | P35462 | 15/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701388 | 0.89 | TACR1 (0.58) | TACR1DRD2DRD3 | |
| SCHEMBL8701895 | 0.88 | TACR1 (0.46) | TACR1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8702034 | 0.87 | TACR1 (0.46) | TACR1DRD2DRD3 | |
| SCHEMBL8703805 | 0.83 | TACR1 (0.47) | TACR1DRD2DRD3 | |
| SCHEMBL8706809 | 0.82 | TACR1 (0.47) | TACR1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8701137 | 0.82 | TACR1 (0.47) | TACR1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8706392 | 0.82 | TACR1 (0.46) | TACR1DRD2DRD3 | |
| SCHEMBL8708219 | 0.81 | DRD2 (0.48) | TACR1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8702405 | 0.80 | DRD2 (0.48) | TACR1DRD2DRD3 | |
| SCHEMBL8707768 | 0.80 | TACR1 (0.48) | TACR1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721255-A | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 1998-02-24 | — | — | US | disclosed |