SCHEMBL8701735

SCHEMBL8701735

O=C(CO)COc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.65
KMT2A Q03164 4/20 0.58
MEN1 O00255 3/20 0.58
ALPL P05186 1/20 0.52
ALPI P09923 1/20 0.52
ALPG P10696 1/20 0.52
ALDH1A1 P00352 2/20 0.50
PLA2G4B P0C869 1/20 0.50
RECQL P46063 1/20 0.50
HPGD P15428 1/20 0.50
GAA P10253 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
USP2 O75604 1/20 0.49
FFAR1 O14842 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MAPT P10636 1/20 0.47
PTPN7 P35236 1/20 0.47
PTPN12 Q05209 1/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9640504 0.89 PLA2G4B (0.50) ALOX15KMT2AMEN1ALDH1A1PLA2G4B
SCHEMBL3898377 0.89 ALOX15 (0.74) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL15396047 0.84 ALOX15 (0.68) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL11956755 0.83 ALOX15 (0.65) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL9824596 0.81 ALOX15 (0.69) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4644360 0.81 ALOX15 (0.63) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL29152112 0.81 ALOX15 (0.63) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL6925228 0.81 ALOX15 (0.63) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4125546 0.81 ALOX15 (0.63) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL464497 0.81 ALOX15 (0.63) ALOX15KMT2AMEN1ALPLALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608320-B1 ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS RICHARDSON VICKS INC (US) 1998-01-28 EP claimed
CN-105163706-A Microcapsules comprising sunscreen agents TAGRA BIOTECHNOLOGIES LTD 2015-12-16 CN disclosed