Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8707886 | 0.99 | TACR1 (0.35) | TACR1DRD2SLC6A3OPRD1OPRK1 | |
| SCHEMBL8706170 | 0.92 | DRD2 (0.34) | TACR1DRD2SLC6A3OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL8706566 | 0.91 | DRD2 (0.33) | TACR1DRD2SLC6A3OPRD1OPRK1 | |
| SCHEMBL8701385 | 0.89 | TACR1 (0.45) | TACR1PTGS2 | |
| SCHEMBL8701299 | 0.86 | TACR1 (0.36) | TACR1PTGS2BRD4CYP19A1 | |
| Hydrochloric Acid SCHEMBL8702143 | 0.86 | TACR1 (0.35) | TACR1PTGS2BRD4CYP19A1 | |
| SCHEMBL8707766 | 0.85 | TACR1 (0.38) | TACR1SLC6A2CYP19A1 | |
| SCHEMBL8705094 | 0.84 | TACR1 (0.35) | TACR1RORCOPRL1 | |
| Hydrochloric Acid SCHEMBL8707618 | 0.83 | TACR1 (0.37) | TACR1CYP19A1 | |
| Hydrochloric Acid SCHEMBL8706672 | 0.83 | TACR1 (0.35) | TACR1RORCOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721255-A | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 1998-02-24 | — | — | US | claimed |
| US-5721255-A | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 1998-02-24 | — | — | US | disclosed |