Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.47 |
| ▸ | DRD2 | P14416 | 9/20 | 0.36 |
| ▸ | DRD3 | P35462 | 7/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706173 | 0.92 | TACR1 (0.40) | TACR1DRD2DRD3SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL8706570 | 0.91 | TACR1 (0.41) | TACR1DRD2DRD3SLC6A3CYP2D6 | |
| SCHEMBL8701388 | 0.89 | TACR1 (0.58) | TACR1DRD2DRD3 | |
| SCHEMBL8707768 | 0.88 | TACR1 (0.48) | TACR1DRD2DRD3 | |
| SCHEMBL8701301 | 0.87 | TACR1 (0.47) | TACR1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8702145 | 0.86 | TACR1 (0.47) | TACR1DRD2DRD3 | |
| SCHEMBL7718909 | 0.81 | TACR1 (0.43) | TACR1SLC6A3CYP2D6KCNH2HTR1A | |
| SCHEMBL8703805 | 0.80 | TACR1 (0.47) | TACR1DRD2DRD3 | |
| SCHEMBL8706809 | 0.79 | TACR1 (0.47) | TACR1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8701137 | 0.79 | TACR1 (0.47) | TACR1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721255-A | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 1998-02-24 | — | — | US | claimed |