Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.42 |
| ▸ | DRD3 | P35462 | 10/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8707079 | 0.99 | DRD2 (0.41) | DRD2DRD3HTTNPSR1L3MBTL1 | |
| SCHEMBL8708219 | 0.91 | DRD2 (0.48) | DRD2DRD3HTTNPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8702405 | 0.90 | DRD2 (0.48) | DRD2DRD3HTTNPSR1L3MBTL1 | |
| SCHEMBL8701301 | 0.88 | TACR1 (0.47) | DRD2DRD3L3MBTL1TACR1 | |
| Hydrochloric Acid SCHEMBL8702145 | 0.88 | TACR1 (0.47) | DRD2DRD3L3MBTL1TACR1ALDH1A1 | |
| SCHEMBL8701076 | 0.83 | TACR1 (0.38) | DRD2DRD3L3MBTL1TACR1LMNA | |
| Hydrochloric Acid SCHEMBL8701615 | 0.83 | TACR1 (0.38) | DRD2DRD3L3MBTL1TACR1LMNA | |
| SCHEMBL8703805 | 0.80 | TACR1 (0.47) | DRD2DRD3TACR1GAA | |
| Hydrochloric Acid SCHEMBL8701137 | 0.79 | TACR1 (0.47) | DRD2DRD3TACR1GAA | |
| SCHEMBL8701388 | 0.79 | TACR1 (0.58) | DRD2DRD3TACR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721255-A | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 1998-02-24 | — | — | US | claimed |