Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 14/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702617 | 0.84 | MEN1 (0.51) | MEN1KMT2ATACR1TACR2TACR3 | |
| SCHEMBL8706204 | 0.82 | MEN1 (0.49) | MEN1KMT2ATACR1TACR2TACR3 | |
| SCHEMBL8703023 | 0.82 | MEN1 (0.45) | MEN1KMT2ATACR1TACR2TACR3 | |
| SCHEMBL8701915 | 0.79 | TACR1 (0.43) | MEN1KMT2ATACR1TACR2TACR3 | |
| SCHEMBL8703039 | 0.79 | TACR2 (0.38) | TACR1TACR2TACR3TDP1 | |
| SCHEMBL4631251 | 0.76 | TACR1 (0.40) | TACR1TACR2TACR3 | |
| SCHEMBL8707339 | 0.76 | TACR1 (0.43) | MEN1KMT2ATACR1TACR2TACR3 | |
| SCHEMBL8703187 | 0.74 | TACR1 (0.55) | TACR1TACR2TACR3 | |
| SCHEMBL8702396 | 0.73 | TACR1 (0.47) | TACR1TACR2TACR3 | |
| SCHEMBL8702880 | 0.73 | TACR1 (0.47) | TACR1TACR2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018762-A1 | NEW DERIVATIVES OF DIVERSELY SUBSTITUTED CYCLICAL AMIDE SELECTIVE ANTAGONISTS OF THE HUMAN RECEPTOR NK3, PROCESS FOR OBTAINING THEM, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1998-05-07 | — | — | WO | disclosed |