Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846541 | 0.82 | TACR1 (0.60) | TACR1TACR2TACR3CCR5 | |
| SCHEMBL4631281 | 0.81 | TACR1 (0.45) | TACR1TACR2TACR3CCR5 | |
| SCHEMBL8706204 | 0.80 | MEN1 (0.49) | TACR1MEN1KMT2ATACR2TACR3 | |
| SCHEMBL8701915 | 0.80 | TACR1 (0.43) | TACR1MEN1KMT2APDE4APDE4B | |
| SCHEMBL8702363 | 0.79 | MEN1 (0.37) | TACR1MEN1KMT2APDE4APDE4B | |
| SCHEMBL8300796 | 0.79 | TACR1 (0.59) | TACR1TACR2TACR3CCR5 | |
| SCHEMBL8702617 | 0.78 | MEN1 (0.51) | TACR1MEN1KMT2ATACR2TACR3 | |
| SCHEMBL7956549 | 0.78 | TACR1 (0.49) | TACR1CCR5 | |
| SCHEMBL4631098 | 0.77 | TACR1 (0.41) | TACR1 | |
| SCHEMBL4630790 | 0.77 | TACR1 (0.44) | TACR1TACR2TACR3CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018762-A1 | NEW DERIVATIVES OF DIVERSELY SUBSTITUTED CYCLICAL AMIDE SELECTIVE ANTAGONISTS OF THE HUMAN RECEPTOR NK3, PROCESS FOR OBTAINING THEM, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1998-05-07 | — | — | WO | disclosed |