Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432368 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAAADGKAMEN1KMT2A | |
| SCHEMBL8433337 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAAADGKAMEN1KMT2A | |
| SCHEMBL8707361 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAAADGKAMEN1KMT2A | |
| SCHEMBL8433929 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAAADGKAMEN1KMT2A | |
| SCHEMBL8430001 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAAADGKAMEN1KMT2A | |
| SCHEMBL8707982 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAAADGKAMEN1KMT2A | |
| SCHEMBL8430031 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAAADGKAMEN1KMT2A | |
| SCHEMBL8704760 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAAADGKAMEN1KMT2A | |
| SCHEMBL8431983 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAAADGKAMEN1KMT2A | |
| SCHEMBL8433938 | 1.00 | L3MBTL1 (0.52) | L3MBTL1NAAADGKAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844000-A1 | Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis | SANKYO COMPANY LIMITED (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0600717-A1 | Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis | SANKYO COMPANY LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |