Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702015 | 0.95 | KMT2A (0.46) | KMT2AKDM4ESLC6A3TOP1PTGES | |
| SCHEMBL7830474 | 0.77 | KDM4E (0.42) | KDM4EMAPTALDH1A1HTT | |
| SCHEMBL7824728 | 0.75 | NPC1 (0.47) | KDM4E | |
| SCHEMBL10786907 | 0.73 | KMT2A (0.56) | KMT2ASLC6A3TOP1MAPTGAA | |
| SCHEMBL8873184 | 0.73 | MAPT (0.40) | KMT2AKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL18380643 | 0.70 | KDM4E (0.61) | KDM4EMAPTALDH1A1HTT | |
| SCHEMBL7827566 | 0.68 | HRH3 (0.46) | KDM4EMAPTHTT | |
| SCHEMBL8873929 | 0.68 | EGFR (0.44) | KDM4EMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6587245 | 0.68 | ALDH1A1 (0.49) | KMT2AKDM4ESLC6A3MAPTALDH1A1 | |
| SCHEMBL11121859 | 0.68 | HSD17B10 (0.58) | KMT2AKDM4ESLC6A3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |