Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 10/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474045 | 0.89 | FOLH1 (0.70) | FOLH1ALDH1A1SLC16A3ALOX15TSHR | |
| SCHEMBL729909 | 0.85 | FOLH1 (0.70) | FOLH1ALDH1A1SLC16A3ALOX15TSHR | |
| SCHEMBL9345842 | 0.83 | FOLH1 (0.68) | FOLH1ALDH1A1SLC16A3ALOX15TSHR | |
| SCHEMBL20162476 | 0.81 | FOLH1 (0.61) | FOLH1ALDH1A1SLC16A3ALOX15TSHR | |
| SCHEMBL8791639 | 0.81 | FOLH1 (0.61) | FOLH1ALDH1A1SLC16A3ALOX15TSHR | |
| SCHEMBL70392 | 0.80 | FOLH1 (0.76) | FOLH1ALDH1A1SLC16A3ALOX15TSHR | |
| SCHEMBL30365583 | 0.80 | FOLH1 (0.76) | FOLH1ALDH1A1SLC16A3ALOX15TSHR | |
| SCHEMBL5806456 | 0.79 | FOLH1 (0.63) | FOLH1ALDH1A1SLC16A3ALOX15TSHR | |
| SCHEMBL11198898 | 0.79 | FOLH1 (0.54) | FOLH1ALDH1A1SLC16A3ALOX15TSHR | |
| SCHEMBL8698803 | 0.79 | FOLH1 (0.58) | FOLH1ALDH1A1SLC16A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834468-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, ANALGESICS TREATING RHEUMATIC DISEASE, BONE DISORDER, INJURIES | ZENECA LIMITED (GB) | 1998-11-10 | — | — | US | disclosed |