Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | BID | P55957 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702953 | 0.94 | FOLH1 (0.63) | FOLH1ALDH1A1ADRB2LMNAKDM4E | |
| SCHEMBL20162476 | 0.93 | FOLH1 (0.61) | FOLH1ALDH1A1ADRB2SMN1; SMN2MAPT | |
| SCHEMBL166927 | 0.93 | FOLH1 (0.66) | FOLH1ALDH1A1ADRB2LMNAKDM4E | |
| SCHEMBL29975597 | 0.93 | FOLH1 (0.66) | FOLH1ALDH1A1ADRB2LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL7699238 | 0.91 | FOLH1 (0.63) | FOLH1ALDH1A1ADRB2LMNAKDM4E | |
| SCHEMBL11710027 | 0.89 | FOLH1 (0.61) | FOLH1ALDH1A1ADRB2SMN1; SMN2MAPT | |
| SCHEMBL31474045 | 0.89 | FOLH1 (0.70) | FOLH1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL8698905 | 0.88 | FOLH1 (0.61) | FOLH1ALDH1A1ADRB2TSHRSLC16A3 | |
| SCHEMBL729909 | 0.85 | FOLH1 (0.70) | FOLH1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL70392 | 0.84 | FOLH1 (0.76) | FOLH1ALDH1A1ADRB2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834468-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, ANALGESICS TREATING RHEUMATIC DISEASE, BONE DISORDER, INJURIES | ZENECA LIMITED (GB) | 1998-11-10 | — | — | US | disclosed |