Isovanillin

Isovanillin

SCHEMBL8703725

COc1ccc(C=O)cc1O.O=Cc1ccc(O)c(O)c1

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.89
AOX1 Q06278 1/20 0.89
TRIM24 O15164 1/20 0.71
HPGD P15428 1/20 0.71
ALDH5A1 P51649 1/20 0.71
ABAT P80404 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
TRIM33 Q9UPN9 1/20 0.71
KDM4E B2RXH2 1/20 0.68
PTGS2 P35354 1/20 0.68
RAB9A P51151 1/20 0.68
TSHR P16473 1/20 0.61
MAPT P10636 3/20 0.59
CYP1A2 P05177 1/20 0.59
APP P05067 2/20 0.57
TUBB1 Q9H4B7 7/20 0.56
ALOX5 P09917 1/20 0.54
NQO1 P15559 1/20 0.54
NQO2 P16083 1/20 0.54
SLC22A2 O15244 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isovanillin SCHEMBL1535672 0.94 ALDH1A1 (1.00) ALDH1A1AOX1TRIM24HPGDALDH5A1
Isovanillin SCHEMBL70256 0.94 ALDH1A1 (1.00) ALDH1A1AOX1TRIM24HPGDALDH5A1
Isovanillin SCHEMBL29396443 0.94 ALDH1A1 (1.00) ALDH1A1AOX1TRIM24HPGDALDH5A1
Vanillin SCHEMBL10854393 0.91 ALDH1A1 (0.86) ALDH1A1AOX1TRIM24HPGDALDH5A1
Isovanillin SCHEMBL28052909 0.91 ALDH1A1 (0.93) ALDH1A1AOX1TRIM24HPGDALDH5A1
Protocatechualdehyde SCHEMBL28302764 0.88 ALDH1A1 (0.70) ALDH1A1AOX1TRIM24HPGDALDH5A1
Isovanillin SCHEMBL15259649 0.88 ALDH1A1 (0.86) ALDH1A1AOX1TRIM24HPGDALDH5A1
Isovanillin SCHEMBL28288925 0.86 ALDH1A1 (0.83) ALDH1A1AOX1TRIM24HPGDALDH5A1
Isovanillin SCHEMBL28288896 0.86 ALDH1A1 (0.83) ALDH1A1AOX1TRIM24HPGDALDH5A1
Isovanillin SCHEMBL8972210 0.85 ALDH1A1 (0.81) ALDH1A1AOX1TRIM24HPGDALDH5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998008813-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES ELI LILLY AND COMPANY (US) 1998-03-05 WO disclosed