Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132286 | 0.87 | KMT2A (0.54) | KMT2AMAPTPOLBMEN1KDM4E | |
| SCHEMBL4110000 | 0.86 | KDM4E (0.53) | KMT2AMAPTPOLBMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL28371347 | 0.86 | KMT2A (0.53) | KMT2AMAPTPOLBMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL28371346 | 0.86 | KMT2A (0.53) | KMT2AMAPTPOLBMEN1KDM4E | |
| SCHEMBL28371204 | 0.83 | KDM4E (0.50) | KMT2AMAPTPOLBMEN1KDM4E | |
| SCHEMBL28371206 | 0.83 | KDM4E (0.50) | KMT2AMAPTPOLBMEN1KDM4E | |
| SCHEMBL27484962 | 0.81 | MAPT (0.59) | KMT2AMAPTPOLBMEN1KDM4E | |
| SCHEMBL27484963 | 0.81 | MAPT (0.59) | KMT2AMAPTPOLBMEN1KDM4E | |
| SCHEMBL8483346 | 0.80 | MMP9 (0.63) | KMT2AMAPTPOLBMEN1KDM4E | |
| SCHEMBL28435992 | 0.79 | KCNT1 (0.51) | KMT2AMAPTPOLBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846942-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1998-12-08 | — | — | US | disclosed |