SCHEMBL870397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL870398	1.00	PDE4B (0.45)	PDE4BHPGDSEGLN1DCKKCNH2
	SCHEMBL870787	0.95	PDE4B (0.46)	PDE4BHPGDSEGLN1DCKKCNH2
	SCHEMBL870786	0.95	PDE4B (0.46)	PDE4BHPGDSEGLN1DCKKCNH2
	SCHEMBL872121	0.93	PDE4B (0.47)	PDE4BHPGDSEGLN1KCNH2PDE4A
	SCHEMBL871984	0.93	PDE4B (0.47)	PDE4BHPGDSEGLN1KCNH2PDE4A
	SCHEMBL870899	0.93	PDE4B (0.47)	PDE4BHPGDSDCKPDE4D
	SCHEMBL870898	0.93	PDE4B (0.47)	PDE4BHPGDSDCKPDE4D
	SCHEMBL870027	0.91	PDE4B (0.45)	PDE4BHPGDSEGLN1KCNH2PDE4A
	SCHEMBL871868	0.91	PDE4B (0.49)	PDE4BHPGDSEGLN1KCNH2PDE4A
	SCHEMBL870026	0.91	PDE4B (0.45)	PDE4BHPGDSEGLN1KCNH2PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.