SCHEMBL870449

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL870450	1.00	AVPR1B (0.43)	AVPR1BSIGMAR1PDE4BAXLFLT3
	SCHEMBL870166	0.99	AVPR1B (0.44)	AVPR1BSIGMAR1PDE4BAXLFLT3
	SCHEMBL870165	0.99	AVPR1B (0.44)	AVPR1BSIGMAR1PDE4BAXLFLT3
	SCHEMBL870299	0.94	AVPR1B (0.39)	AVPR1BPDE4BAXLFLT3TYRO3
	SCHEMBL870300	0.94	AVPR1B (0.39)	AVPR1BPDE4BAXLFLT3TYRO3
	SCHEMBL3030807	0.92	AVPR1B (0.41)	AVPR1BPDE4BAXLFLT3TYRO3
	SCHEMBL3030814	0.92	AVPR1B (0.41)	AVPR1BPDE4BAXLFLT3TYRO3
	SCHEMBL3019156	0.92	AVPR1B (0.39)	AVPR1BSIGMAR1PDE4BAXLFLT3
	SCHEMBL870180	0.92	AVPR1B (0.41)	AVPR1BPDE4BDYRK1AWNT1ADRB2
	SCHEMBL8170394	0.92	AVPR1B (0.39)	AVPR1BSIGMAR1PDE4BAXLFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.