SCHEMBL870526

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL870527	1.00	PDE4B (0.45)	PDE4BKCNH2CYP3A4CYP2C9CYP2C19
	SCHEMBL3023252	0.89	KCNH2 (0.35)	PDE4BKCNH2CNR2MAP4K4
	SCHEMBL3023254	0.89	KCNH2 (0.35)	PDE4BKCNH2CNR2MAP4K4
	SCHEMBL3029903	0.88	PDE4B (0.47)	PDE4BKCNH2CYP3A4CYP2C9CYP2C19
	SCHEMBL870745	0.88	PDE4B (0.46)	PDE4BKCNH2CYP3A4CYP2C9CYP2C19
	SCHEMBL871627	0.88	PDE4B (0.47)	PDE4BKCNH2CYP3A4CYP2C9CYP2C19
	SCHEMBL870458	0.88	PDE4B (0.49)	PDE4BKCNH2CYP2C19CNR2CNR1
	SCHEMBL870459	0.88	PDE4B (0.49)	PDE4BKCNH2CYP2C19CNR2CNR1
	SCHEMBL8183839	0.88	PDE4B (0.49)	PDE4BKCNH2CYP2C19CNR2CNR1
	SCHEMBL870970	0.87	PDE4B (0.47)	PDE4BKCNH2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.