SCHEMBL8705296

SCHEMBL8705296

CCC(C)(C)[C@H]1CC[C@H](OS(=O)(=O)c2ccc(C)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.51
CYP3A4 P08684 1/20 0.47
CYP2C19 P33261 1/20 0.47
CYP1A2 P05177 1/20 0.43
ALDH1A1 P00352 5/20 0.38
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 4/20 0.37
MEN1 O00255 2/20 0.37
RAB9A P51151 1/20 0.37
HSD11B1 P28845 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
S1PR5 Q9H228 1/20 0.34
HTR6 P50406 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8705300 1.00 CYP2D6 (0.51) CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1
SCHEMBL8710398 0.88 CYP2D6 (0.50) CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1
SCHEMBL8710401 0.88 CYP2D6 (0.50) CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1
SCHEMBL8710931 0.88 CYP2D6 (0.50) CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1
SCHEMBL4411763 0.85 CYP3A4 (0.57) CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1
SCHEMBL3391969 0.85 CYP3A4 (0.57) CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1
SCHEMBL10409067 0.85 CYP2D6 (0.56) CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1
SCHEMBL4411239 0.85 CYP3A4 (0.57) CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1
SCHEMBL657896 0.83 CYP2D6 (0.67) CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1
SCHEMBL10376015 0.83 CYP2D6 (0.67) CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723450-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1998-03-03 US disclosed
US-5650417-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-07-22 US disclosed
EP-0719255-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
EP-0719256-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
WO-1995007891-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed
WO-1995007890-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed