Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705390 | 1.00 | S1PR5 (0.40) | S1PR5GRM2IDO1ARSLC6A4 | |
| SCHEMBL8705541 | 0.83 | GRM2 (0.38) | S1PR5GRM2IDO1HTR1AADRA2A | |
| SCHEMBL8705538 | 0.83 | GRM2 (0.38) | S1PR5GRM2IDO1HTR1AADRA2A | |
| SCHEMBL8415227 | 0.78 | MAPT (0.39) | S1PR5IDO1AR | |
| SCHEMBL8415224 | 0.78 | MAPT (0.39) | S1PR5IDO1AR | |
| SCHEMBL17730126 | 0.76 | IDO1 (0.37) | IDO1ARKMOTLR9TLR8 | |
| SCHEMBL17730123 | 0.76 | IDO1 (0.37) | IDO1ARKMOTLR9TLR8 | |
| SCHEMBL18016750 | 0.75 | GRM2 (0.36) | S1PR5GRM2IDO1ARHTR1A | |
| SCHEMBL17985228 | 0.75 | GRM2 (0.53) | S1PR5GRM2IDO1SLC6A4 | |
| SCHEMBL17985229 | 0.75 | GRM2 (0.53) | S1PR5GRM2IDO1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723450-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0719256-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007891-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |