SCHEMBL8415224

SCHEMBL8415224

Cc1nccc(OC2CCC(C(C)(C)C)CC2)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
S1PR5 Q9H228 14/20 0.38
CYP19A1 P11511 1/20 0.36
FGFR2 P21802 1/20 0.34
ENPP2 Q13822 1/20 0.34
IDO1 P14902 1/20 0.33
AR P10275 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8415227 1.00 MAPT (0.39) MAPTS1PR5CYP19A1FGFR2ENPP2
SCHEMBL8706582 0.88 ACACB (0.36) IDO1AR
SCHEMBL8414972 0.82 MAPT (0.38) MAPTS1PR5CYP19A1FGFR2ENPP2
SCHEMBL8414973 0.82 MAPT (0.38) MAPTS1PR5CYP19A1FGFR2ENPP2
SCHEMBL8705388 0.78 S1PR5 (0.40) S1PR5IDO1AR
SCHEMBL8705390 0.78 S1PR5 (0.40) S1PR5IDO1AR
SCHEMBL17730123 0.78 IDO1 (0.37) IDO1AR
SCHEMBL17730126 0.78 IDO1 (0.37) IDO1AR
SCHEMBL8519672 0.76 IDO1 (0.42) IDO1AR
SCHEMBL24188521 0.75 SLC6A4 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5877322-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1999-03-02 US disclosed