Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703413 | 0.82 | CYP1A2 (0.61) | HTR7MAOAMAOBCYP1A2ALDH1A1 | |
| SCHEMBL30421706 | 0.82 | CYP1A2 (0.61) | HTR7MAOAMAOBCYP1A2ALDH1A1 | |
| SCHEMBL6299141 | 0.81 | HTR7 (0.46) | HTR7MAOAMAOBCYP1A2ALDH1A1 | |
| SCHEMBL30184557 | 0.81 | HTR7 (0.46) | HTR7MAOAMAOBCYP1A2ALDH1A1 | |
| SCHEMBL30421739 | 0.81 | HTR7 (0.44) | HTR7MAOAMAOBCYP1A2ALDH1A1 | |
| SCHEMBL15916105 | 0.81 | SMN1; SMN2 (0.52) | HTR7MAOAMAOBCYP1A2ALDH1A1 | |
| SCHEMBL27044922 | 0.78 | CYP1A2 (0.43) | CYP1A2ALDH1A1MAPTHSD17B10POLB | |
| SCHEMBL27044923 | 0.78 | HSD17B10 (0.62) | CYP1A2ALDH1A1MAPTHSD17B10POLB | |
| SCHEMBL27044925 | 0.78 | NOTUM (0.50) | CYP1A2ALDH1A1MAPTHSD17B10POLB | |
| SCHEMBL23149012 | 0.78 | HTR7 (0.42) | HTR7MAOAMAOBCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998033793-A1 | α-AZACYCLOMETHYL BENZOTHIOPHENE AND α-AZACYCLOMETHYL BENZOFURANE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION | SANOFI-SYNTHELABO (FR) | 1998-08-06 | — | — | WO | disclosed |