Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706557 | 1.00 | KLK7 (0.45) | KLK7F2RL3ALOX5APFEN1TSHR | |
| SCHEMBL8706834 | 0.89 | CHEK2 (0.44) | KLK7TSHRPRMT5HCRTR2MEN1 | |
| SCHEMBL8702684 | 0.89 | TP53 (0.49) | TSHR | |
| SCHEMBL8702640 | 0.89 | TP53 (0.49) | TSHR | |
| SCHEMBL8702646 | 0.89 | TP53 (0.49) | TSHR | |
| SCHEMBL8708341 | 0.87 | F2RL3 (0.42) | F2RL3ALOX5APFEN1TSHR | |
| SCHEMBL8703526 | 0.87 | F2RL3 (0.42) | F2RL3ALOX5APFEN1TSHR | |
| SCHEMBL9413620 | 0.86 | ALOX5AP (0.44) | F2RL3ALOX5APFEN1TSHRMEN1 | |
| SCHEMBL9413621 | 0.86 | ALOX5AP (0.44) | F2RL3ALOX5APFEN1TSHRMEN1 | |
| SCHEMBL29039347 | 0.84 | F2RL3 (0.45) | F2RL3ALOX5APFEN1TSHROPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844000-A1 | Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis | SANKYO COMPANY LIMITED (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |