Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413621 | 1.00 | ALOX5AP (0.44) | ALOX5APFEN1F2RL3CHRNB4CHRNA3 | |
| SCHEMBL8706557 | 0.86 | KLK7 (0.45) | ALOX5APFEN1F2RL3TSHRALDH1A1 | |
| SCHEMBL8706554 | 0.86 | KLK7 (0.45) | ALOX5APFEN1F2RL3TSHRALDH1A1 | |
| SCHEMBL2200755 | 0.86 | CHRNB4 (0.58) | ALOX5APFEN1F2RL3CHRNB4CHRNA3 | |
| SCHEMBL8702640 | 0.85 | TP53 (0.49) | ABCB1TSHRMAPK1 | |
| SCHEMBL8702684 | 0.85 | TP53 (0.49) | ABCB1TSHRMAPK1 | |
| SCHEMBL8702646 | 0.85 | TP53 (0.49) | ABCB1TSHRMAPK1 | |
| SCHEMBL29039347 | 0.82 | F2RL3 (0.45) | ALOX5APFEN1F2RL3CHRNB4CHRNA3 | |
| SCHEMBL26999499 | 0.82 | F2RL3 (0.45) | ALOX5APFEN1F2RL3CHRNB4CHRNA3 | |
| SCHEMBL8708341 | 0.82 | F2RL3 (0.42) | ALOX5APFEN1F2RL3ABCB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600717-A1 | Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis | SANKYO COMPANY LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |