SCHEMBL87071

SCHEMBL87071

O=C1CCOc2c(Cl)cc(I)cc21

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.37
MAOA P21397 1/20 0.37
GRM5 P41594 2/20 0.32
NOTUM Q6P988 1/20 0.31
VHL P40337 1/20 0.30
ELOC Q15369 1/20 0.30
ELOB Q15370 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67615 0.82 MEN1 (0.46) MAOBMAOAGRM5NOTUMVHL
SCHEMBL30543406 0.82 MEN1 (0.46) MAOBMAOAGRM5NOTUMVHL
SCHEMBL10741838 0.79 SIRT2 (0.44) MAOBMAOAGRM5NOTUMVHL
SCHEMBL8191575 0.76 MAOB (0.37) MAOBMAOAGRM5VHLELOC
SCHEMBL6582780 0.76 MAPT (0.39) MAOBMAOAGRM5
SCHEMBL29222599 0.76 MAOB (0.34) MAOBMAOAGRM5
SCHEMBL11483580 0.74 GRM5 (0.40) MAOBMAOAGRM5MEN1KMT2A
Hydrochloric Acid SCHEMBL7401466 0.73 MAPT (0.38) MAOBMAOAGRM5
SCHEMBL7401468 0.72 MAPT (0.37) MAOBMAOAGRM5
SCHEMBL768960 0.71 MAPT (0.46) MAOBMAOAGRM5NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20100285232-A1 PROCESS FOR PRODUCING AN OVERPRINT FUJIFILM CORPORATION (JP) 2010-11-11 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
WO-2000021949-A1 QUINOLONES AS T-RNA SYNTHETASE INHIBITORS AND ANTIBACTERIAL AGENTS SMITHKLINE BEECHAM PLC (GB) 2000-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 MAOB 202/4885MAOA 415/4885GRM5 2547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.