Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183886 | 0.83 | SRD5A1 (0.53) | SRD5A1CYP19A1 | |
| SCHEMBL5183889 | 0.83 | SRD5A1 (0.53) | SRD5A1CYP19A1 | |
| SCHEMBL4619444 | 0.79 | CYP19A1 (0.46) | CYP19A1 | |
| SCHEMBL7529519 | 0.78 | CYP19A1 (0.58) | SRD5A1CYP19A1 | |
| SCHEMBL3797856 | 0.78 | CYP19A1 (0.58) | SRD5A1CYP19A1 | |
| SCHEMBL9318216 | 0.77 | SRD5A1 (0.61) | SRD5A1CYP19A1 | |
| SCHEMBL9939642 | 0.76 | CYP19A1 (0.60) | CYP19A1 | |
| SCHEMBL5907009 | 0.76 | SRD5A1 (0.49) | SRD5A1CYP19A1 | |
| SCHEMBL13970856 | 0.76 | SRD5A1 (0.54) | SRD5A1CYP19A1 | |
| SCHEMBL7617295 | 0.75 | SRD5A1 (0.64) | SRD5A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880540-A1 | 17-BETA-CYCLOPROPYL(AMINO/OXY) 4-AZA STEROIDS AS ACTIVE INHIBITORS OF TESTOSTERONE 5-ALPHA-REDUCTASE AND C17-20-LYASE | HOECHST MARION ROUSSEL, INC. (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997030069-A1 | 17-BETA-CYCLOPROPYL(AMINO/OXY) 4-AZA STEROIDS AS ACTIVE INHIBITORS OF TESTOSTERONE 5-ALPHA-REDUCTASE AND C17-20-LYASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-08-21 | — | — | WO | disclosed |