Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14052473 | 0.82 | NPC1 (0.54) | MAOBMAOALMNACYP3A4KDM4E | |
| SCHEMBL2209825 | 0.81 | TSHR (0.58) | MAOBMAOALMNAKDM4ENPC1 | |
| SCHEMBL2907025 | 0.79 | KDM4E (0.62) | MAOBMAOALMNAKDM4ENPC1 | |
| SCHEMBL18506191 | 0.78 | LMNA (0.66) | MAOBMAOALMNACYP3A4KDM4E | |
| SCHEMBL27468894 | 0.78 | NPC1 (0.58) | MAOBMAOANPC1RAB9AALDH1A1 | |
| SCHEMBL7349348 | 0.77 | LMNA (0.78) | MAOBMAOALMNAKDM4ENPC1 | |
| SCHEMBL29366799 | 0.77 | NPC1 (0.58) | MAOBLMNAKDM4ENPC1RAB9A | |
| SCHEMBL28512382 | 0.77 | NPC1 (0.58) | MAOBLMNAKDM4ENPC1RAB9A | |
| SCHEMBL18015826 | 0.76 | MAOB (0.57) | MAOBMAOACYP3A4KDM4ENPC1 | |
| SCHEMBL10155752 | 0.76 | FLT3 (0.67) | LMNAKDM4ENPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10237089-A | — | — | None | — | — | JP | disclosed |
| JP-H10237089-A | PROPIOPHENONE DERIVATIVE AND ITS PRODUCTION | TANABE SEIYAKU CO LTD | 1998-09-08 | — | — | JP | disclosed |