Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 17/20 | 0.53 |
| ▸ | HTR1B | P28222 | 15/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR1F | P30939 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713578 | 0.97 | SLC6A4 (0.52) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8383600 | 0.94 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8706176 | 0.91 | HTR1D (0.47) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| Phenyl Propionic Acid SCHEMBL8706174 | 0.91 | HTR1D (0.47) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8386450 | 0.91 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8385368 | 0.89 | HTR1D (0.56) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8387309 | 0.89 | HTR1D (0.50) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8382853 | 0.88 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8387149 | 0.88 | SLC6A4 (0.58) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8385424 | 0.88 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR1FSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998046570-A1 | SUBSTITUTED HETEROAROMATIC 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |