Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | BRAP | Q7Z569 | 1/20 | 0.34 |
| ▸ | USP16 | Q9Y5T5 | 1/20 | 0.34 |
| ▸ | USP3 | Q9Y6I4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499418 | 0.83 | HDAC6 (0.46) | TBXA2RLMNAHDAC6USP5BRAP | |
| SCHEMBL8708279 | 0.68 | TBXA2R (0.54) | TBXA2RHDAC6KDM4EALDH1A1GAA | |
| SCHEMBL499416 | 0.64 | HDAC6 (0.54) | LMNAHDAC6KDM4EALDH1A1 | |
| SCHEMBL1430689 | 0.60 | MEN1 (0.46) | ALDH1A1 | |
| SCHEMBL8779876 | 0.59 | — | — | |
| SCHEMBL21977323 | 0.58 | PNP (0.54) | TBXA2RLMNAALDH1A1 | |
| SCHEMBL5394795 | 0.57 | TBXA2R (0.61) | TBXA2RKDM4EALDH1A1 | |
| SCHEMBL23077757 | 0.57 | SMN1; SMN2 (0.43) | LMNAHDAC6ALDH1A1 | |
| SCHEMBL12102425 | 0.56 | HDAC6 (0.66) | TBXA2RHDAC6KDM4EALDH1A1GAA | |
| SCHEMBL9753475 | 0.55 | SMN1; SMN2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879238-A1 | BENZIMIDAZOLE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997025335-A1 | BENZIMIDAZOLE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |