Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499416 | 0.76 | HDAC6 (0.54) | KDM4EALDH1A1HDAC6PIN1 | |
| SCHEMBL9005993 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1HDAC6 | |
| SCHEMBL499964 | 0.72 | MEN1 (0.46) | ALDH1A1 | |
| SCHEMBL1430689 | 0.72 | MEN1 (0.46) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4889627 | 0.71 | MEN1 (0.45) | ALDH1A1 | |
| Propionic Acid SCHEMBL25431974 | 0.68 | BACE1 (0.51) | TBXA2RKDM4EALDH1A1 | |
| SCHEMBL8708288 | 0.68 | FBP1 (0.41) | TBXA2RKDM4EALDH1A1GAAHDAC6 | |
| SCHEMBL5394795 | 0.65 | TBXA2R (0.61) | TBXA2RKDM4EALDH1A1 | |
| SCHEMBL499418 | 0.65 | HDAC6 (0.46) | TBXA2RHDAC6PIN1 | |
| SCHEMBL7885451 | 0.65 | KMT2A (0.62) | TBXA2RKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879238-A1 | BENZIMIDAZOLE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997025335-A1 | BENZIMIDAZOLE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |