Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 1/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.50 |
| ▸ | CCKAR | P32238 | 1/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332432 | 0.85 | IL1RN (0.56) | IL1RNERAP2OPRD1OPRM1CCKBR | |
| SCHEMBL29822635 | 0.78 | ERAP2 (0.74) | IL1RNERAP2OPRD1OPRM1KISS1R | |
| SCHEMBL30669510 | 0.77 | EPHX2 (0.61) | EPHX2 | |
| SCHEMBL30845362 | 0.76 | ERAP2 (0.71) | IL1RNERAP2OPRD1OPRM1 | |
| SCHEMBL29593980 | 0.76 | OPRD1 (0.68) | OPRD1OPRM1CCKBRNPBWR1CCKAR | |
| SCHEMBL25627229 | 0.76 | ECE1 (0.63) | IL1RNERAP2KISS1R | |
| SCHEMBL29993798 | 0.76 | OPRD1 (0.65) | IL1RNERAP2OPRD1OPRM1CCKBR | |
| SCHEMBL28544119 | 0.75 | IL1RN (0.64) | IL1RNERAP2OPRD1OPRM1CCKBR | |
| SCHEMBL28544120 | 0.75 | IL1RN (0.64) | IL1RNERAP2OPRD1OPRM1CCKBR | |
| SCHEMBL15692405 | 0.74 | ECE1 (0.71) | IL1RNERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552489-B1 | Peptide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-03-04 | — | — | EP | disclosed |
| US-5614497-A | TREATMENT OF HYPERTENSION, CARDIOVASCULAR DISEASE AND RENAL DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0552489-A2 | Peptide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |