Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 14/20 | 0.68 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920256 | 0.81 | LMNA (0.54) | DDB1CRBNTP53MDM2LMNA | |
| SCHEMBL21934060 | 0.81 | CRBN (0.68) | DDB1CRBNPOLB | |
| SCHEMBL26641271 | 0.81 | CRBN (0.68) | DDB1CRBNPOLB | |
| SCHEMBL31607921 | 0.81 | CRBN (0.68) | DDB1CRBNPOLB | |
| SCHEMBL24848417 | 0.81 | CRBN (0.68) | DDB1CRBNPOLB | |
| SCHEMBL24548260 | 0.81 | CRBN (1.00) | DDB1CRBNPOLB | |
| SCHEMBL30993782 | 0.81 | CRBN (0.68) | DDB1CRBNPOLB | |
| SCHEMBL7827796 | 0.80 | CRBN (0.70) | DDB1CRBNPOLB | |
| Hydrochloric Acid SCHEMBL25204069 | 0.80 | CRBN (0.97) | DDB1CRBNPOLB | |
| SCHEMBL30830763 | 0.80 | CRBN (0.67) | DDB1CRBNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |