SCHEMBL8708409

SCHEMBL8708409

C=Cc1ccc(OC(=O)c2ccc(O)cc2O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.50
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA7 P43166 4/20 0.50
CA9 Q16790 4/20 0.50
CA14 Q9ULX7 4/20 0.50
PDK2 Q15119 1/20 0.50
PDK4 Q16654 1/20 0.50
SERPINE1 P05121 1/20 0.49
CYP3A4 P08684 4/20 0.48
MAPT P10636 4/20 0.48
KMT2A Q03164 4/20 0.48
LMNA P02545 3/20 0.48
TP53 P04637 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 3/20 0.48
ALOX15 P16050 3/20 0.48
HSD17B10 Q99714 3/20 0.48
MEN1 O00255 3/20 0.48
MAPK1 P28482 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9010718 0.85 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL9472028 0.81 HPGD (0.67) CYP3A4MAPTKMT2ALMNATP53
SCHEMBL8835643 0.80 PDK2 (0.64) CA12CA1CA2CA7CA9
SCHEMBL10608463 0.80 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL10611188 0.80 MAPT (0.61) CA12CA1CA2CA7CA9
SCHEMBL4201347 0.79 MAPT (0.71) CA12CA1CA2CA7CA9
SCHEMBL2281149 0.78 CA12 (0.69) CA12CA1CA2CA7CA9
SCHEMBL20695774 0.78 KMT2A (0.49) CA12CA1CA2CA7CA9
SCHEMBL15153710 0.77 MAPT (0.52) CYP3A4MAPTKMT2ALMNATP53
SCHEMBL29560106 0.76 MEN1 (0.62) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0503674-B1 Light-sensitive bistrihalomethyl-s-triazine compound and photopolymerizable composition containing same FUJI PHOTO FILM CO LTD (JP) 1998-06-24 EP disclosed
US-5484682-A FREE RADICAL INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1996-01-16 US disclosed
US-5362874-A Storage stability, discoloration inhibition FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US disclosed
EP-0503674-A1 Light-sensitive bistrihalomethyl-S-triazine compound and photopolymerizable composition containing same FUJI PHOTO FILM CO., LTD. (JP) 1992-09-16 EP disclosed