Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.58 |
| ▸ | CCR5 | P51681 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL948677 | 0.77 | GFER (0.71) | GFERAVPR1ACCR5HTTMAPK14 | |
| SCHEMBL289605 | 0.76 | POLB (0.74) | GFERAVPR1AHTTMAPK14POLB | |
| SCHEMBL8710700 | 0.76 | AVPR1A (0.65) | GFERAVPR1ACCR5HTTMAPK14 | |
| SCHEMBL28481273 | 0.75 | GFER (0.68) | GFERAVPR1ACCR5HTTMAPK14 | |
| SCHEMBL1144650 | 0.75 | GFER (0.68) | GFERAVPR1ACCR5HTTMAPK14 | |
| SCHEMBL8710647 | 0.75 | GFER (0.61) | GFERAVPR1ACCR5HTTMAPK14 | |
| SCHEMBL8445235 | 0.75 | GFER (1.00) | GFERAVPR1AHTTMAPK14MAPT | |
| SCHEMBL13774957 | 0.74 | CA12 (0.59) | GFERCA12CA1CA2CA7 | |
| SCHEMBL2636624 | 0.74 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28978304 | 0.74 | MAPK14 (0.65) | GFERAVPR1ACCR5HTTMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998028292-A1 | NOVEL PIPERIDINE CONTAINING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-02 | — | — | WO | disclosed |