Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77302 | 0.83 | — | — | |
| SCHEMBL29287170 | 0.81 | DAO (0.95) | DAOALDH1A1POLBKMT2ATDP1 | |
| SCHEMBL6561680 | 0.81 | DAO (0.95) | DAOALDH1A1POLBKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL3049773 | 0.81 | DAO (0.95) | DAOALDH1A1POLBKMT2ATDP1 | |
| Formaldehyde SCHEMBL27454853 | 0.79 | DAO (0.91) | DAOALDH1A1POLBKMT2ATDP1 | |
| SCHEMBL7783292 | 0.74 | DAO (0.80) | DAOALDH1A1POLBKMT2ATDP1 | |
| SCHEMBL6487220 | 0.72 | DAO (0.76) | DAOALDH1A1POLBKMT2APKM | |
| SCHEMBL20370914 | 0.71 | DAO (0.73) | DAOALDH1A1POLBKMT2APKM | |
| Terephthalic Acid SCHEMBL4633354 | 0.69 | TSHR (0.57) | DAOALDH1A1CRBN | |
| Succinimide SCHEMBL11381109 | 0.68 | CRBN (0.65) | ALDH1A1TDP1LMNAPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849693-A | Cyclic compounds linked by a heterocyclic ring useful as inhibitors of platelet glycoprotein IIb/IIIa | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |