Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 2/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | GJA1 | P17302 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.43 |
| ▸ | CDC25B | P30305 | 6/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155844 | 0.93 | GJB2 (0.52) | GJB2NT5EGJA1SLC6A2TACR2 | |
| SCHEMBL4421768 | 0.91 | NT5E (0.48) | GJB2NT5ESLC6A2TACR2PTPN1 | |
| SCHEMBL7567428 | 0.91 | SLC6A2 (0.47) | GJB2NT5ESLC6A2PTPN1CDC25B | |
| SCHEMBL27828449 | 0.91 | NT5E (0.48) | GJB2NT5ESLC6A2TACR2PTPN1 | |
| SCHEMBL7567425 | 0.91 | SLC6A2 (0.47) | GJB2NT5ESLC6A2PTPN1CDC25B | |
| SCHEMBL20139723 | 0.91 | SLC6A2 (0.47) | GJB2NT5ESLC6A2PTPN1CDC25B | |
| SCHEMBL2589252 | 0.91 | NT5E (0.48) | GJB2NT5ESLC6A2TACR2PTPN1 | |
| SCHEMBL19731779 | 0.91 | NT5E (0.48) | GJB2NT5ESLC6A2TACR2PTPN1 | |
| SCHEMBL22683015 | 0.91 | SLC6A2 (0.47) | GJB2NT5ESLC6A2PTPN1CDC25B | |
| SCHEMBL6265877 | 0.89 | SSTR1 (0.52) | NT5EPTPN1CDC25BPTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753631-A | Intercellular adhesion mediators | CYTEL CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| US-5576305-A | Intercellular adhesion mediators | CYTEL CORPORATION (US) | 1996-11-19 | — | — | US | disclosed |