Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | BCKDK | O14874 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12748045 | 0.71 | KDM4E (0.61) | MAPTKDM4EBCKDKMCL1RXFP1 | |
| SCHEMBL8285035 | 0.70 | MCL1 (0.44) | MAPTKMT2AKDM4EBCKDKMCL1 | |
| SCHEMBL1155667 | 0.69 | KDM4E (0.80) | MAPTKMT2AKDM4EBCKDKMCL1 | |
| SCHEMBL788639 | 0.69 | NPSR1 (0.48) | MAPTKMT2ABCKDKMCL1RXFP1 | |
| SCHEMBL4917246 | 0.68 | MCL1 (0.40) | MAPTKMT2AKDM4EBCKDKMCL1 | |
| SCHEMBL11661083 | 0.68 | KDM4E (0.66) | MAPTKMT2AKDM4EMCL1GAA | |
| SCHEMBL4922527 | 0.68 | BCKDK (0.53) | MAPTKMT2AKDM4EBCKDKMCL1 | |
| SCHEMBL31228783 | 0.68 | BCKDK (0.53) | MAPTKMT2AKDM4EBCKDKMCL1 | |
| SCHEMBL16934958 | 0.67 | MCL1 (0.42) | MAPTKMT2AKDM4EBCKDKMCL1 | |
| SCHEMBL12153769 | 0.66 | MCL1 (0.71) | MAPTBCKDKMCL1RXFP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027080-A1 | CHROMONES USEFUL AS FUNGICIDES | AGREVO UK LIMITED (GB) | 1998-06-25 | — | — | WO | disclosed |