Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704325 | 0.69 | TP53 (0.49) | ALDH1A1HTTMEN1KMT2APOLB | |
| SCHEMBL29851140 | 0.69 | CYP3A4 (0.49) | CYP2C19CYP3A4CYP2C9ALDH1A1HTT | |
| SCHEMBL23480043 | 0.69 | CYP3A4 (0.49) | CYP2C19CYP3A4CYP2C9ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL8704174 | 0.68 | TP53 (0.48) | ALDH1A1HTTMEN1KMT2APOLB | |
| SCHEMBL24658837 | 0.66 | CYP2C19 (0.46) | CYP2C19CYP3A4CYP2C9ALDH1A1HTT | |
| SCHEMBL8706878 | 0.65 | ACHE (0.54) | CYP3A4ALDH1A1ACHEPOLB | |
| SCHEMBL23479973 | 0.64 | CYP3A4 (0.59) | CYP2C19CYP3A4CYP2C9ALDH1A1HTT | |
| SCHEMBL3558550 | 0.60 | ERN1 (0.47) | ALDH1A1HTTACHEMEN1KMT2A | |
| SCHEMBL3558547 | 0.60 | ACHE (0.46) | CYP2C19CYP3A4CYP2C9USP2ALDH1A1 | |
| SCHEMBL2611542 | 0.59 | ACHE (0.65) | CYP2C19CYP3A4CYP2C9USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731340-A | DIETETICS; ANTIDIABETIC AGENTS | SANOFI (FR) | 1998-03-24 | — | — | US | disclosed |
| CN-1131144-A | Glycinamide derivatives, processes for their preparation and medicines containing them | SANOFI SA (FR) | 1996-09-18 | — | — | CN | disclosed |