Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675844 | 0.74 | TTR (0.46) | TTRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8709921 | 0.72 | ADORA3 (0.46) | TTRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8715528 | 0.70 | TTR (0.42) | TTRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8710058 | 0.69 | AKR1B1 (0.46) | TTRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11324534 | 0.64 | MCL1 (0.57) | TTRKCNH2MEN1KMT2ANPC1 | |
| SCHEMBL10515077 | 0.64 | MAPT (0.50) | KCNH2MEN1KMT2AKDM4ECSNK2A1 | |
| SCHEMBL4092241 | 0.63 | TTR (0.71) | TTRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5677180 | 0.62 | APP (0.36) | TTRNPC1RAB9AALDH1A1NQO1 | |
| SCHEMBL5680363 | 0.62 | KMT2A (0.42) | KMT2AKDM4EMAPK1PIM1CSNK2A1 | |
| SCHEMBL21858350 | 0.62 | MCL1 (0.80) | TTRKCNH2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027080-A1 | CHROMONES USEFUL AS FUNGICIDES | AGREVO UK LIMITED (GB) | 1998-06-25 | — | — | WO | disclosed |