Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 7/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.39 |
| ▸ | CTRC | Q99895 | 4/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710635 | 0.90 | F2 (0.41) | HSD11B1F2PRSS2CTRCHCRTR2 | |
| SCHEMBL8716517 | 0.88 | TSHR (0.43) | F2PRSS2CTRCCYP1A2CYP3A4 | |
| SCHEMBL8712194 | 0.87 | HSD11B1 (0.43) | HSD11B1F2PRSS2CTRCNFE2L2 | |
| SCHEMBL8710883 | 0.87 | TSHR (0.45) | F2PRSS2CTRCCYP1A2CYP3A4 | |
| SCHEMBL8714225 | 0.87 | TSHR (0.45) | F2PRSS2CTRCCYP1A2CYP3A4 | |
| SCHEMBL8711030 | 0.87 | TSHR (0.45) | F2PRSS2CTRCCYP1A2CYP3A4 | |
| SCHEMBL8711068 | 0.87 | TSHR (0.45) | F2PRSS2CTRCCYP1A2CYP3A4 | |
| SCHEMBL8710602 | 0.87 | TSHR (0.45) | F2PRSS2CTRCCYP1A2CYP3A4 | |
| SCHEMBL16045767 | 0.87 | CA1 (0.43) | HTT | |
| SCHEMBL29415291 | 0.87 | CA1 (0.43) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5717124-A | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |