Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | KLK7 | P49862 | 1/20 | 0.57 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27726223 | 0.91 | TACR1 (0.56) | TACR1KLK7CTSLCTSSCTSK | |
| SCHEMBL27705684 | 0.91 | TACR1 (0.56) | TACR1KLK7CTSLCTSSCTSK | |
| SCHEMBL28770050 | 0.90 | CTSL (0.58) | TACR1KLK7CTSLCTSSCTSK | |
| SCHEMBL28770048 | 0.90 | CTSL (0.58) | TACR1KLK7CTSLCTSSCTSK | |
| SCHEMBL10842684 | 0.81 | ACE (0.53) | CTSLACEHDAC8 | |
| SCHEMBL5355362 | 0.81 | TACR1 (0.82) | TACR1KLK7KLK5CTSLCTSS | |
| SCHEMBL8697113 | 0.81 | TACR1 (0.82) | TACR1KLK7KLK5CTSLCTSS | |
| SCHEMBL29397912 | 0.81 | TACR1 (0.82) | TACR1KLK7KLK5CTSLCTSS | |
| SCHEMBL16464197 | 0.81 | TACR1 (0.82) | TACR1KLK7KLK5CTSLCTSS | |
| SCHEMBL22962231 | 0.79 | HDAC8 (0.58) | KLK5CTSLCTSSCTSKACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10182613-A | — | — | None | — | — | JP | disclosed |
| JP-H10182613-A | TETRAPHYDROISOQUINOLINE DERIVATIVE | TANABE SEIYAKU CO LTD | 1998-07-07 | — | — | JP | disclosed |