Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 14/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.42 |
| ▸ | PDE4A | P27815 | 11/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.35 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414973 | 0.79 | MAPT (0.38) | MAOA | |
| SCHEMBL8414972 | 0.79 | MAPT (0.38) | MAOA | |
| SCHEMBL8705538 | 0.77 | GRM2 (0.38) | PDE4BPDE4DPDE4APDE4CMAOA | |
| SCHEMBL8705541 | 0.77 | GRM2 (0.38) | PDE4BPDE4DPDE4APDE4CMAOA | |
| SCHEMBL8708934 | 0.76 | GRM1 (0.36) | PDE4BPDE4DPDE4APDE4CMAOA | |
| Hydrochloric Acid SCHEMBL8708322 | 0.75 | MAOA (0.37) | PDE4BPDE4DPDE4APDE4CMAOA | |
| SCHEMBL8705580 | 0.75 | S1PR5 (0.38) | MAOA | |
| SCHEMBL9033164 | 0.74 | MAOA (0.33) | PDE4BPDE4DPDE4AMAOA | |
| SCHEMBL21176838 | 0.74 | PDGFRA (0.49) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL9034469 | 0.73 | MAOA (0.31) | PDE4DMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723450-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0719256-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007891-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |