Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 6/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5767071 | 0.86 | KDM4E (0.62) | HTR1ADRD2HTR2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL29282529 | 0.85 | KDM4E (0.65) | HTR1ADRD2HTR2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL30890993 | 0.85 | KDM4E (0.65) | HTR1ADRD2HTR2AMAPTKDM4E | |
| SCHEMBL30579531 | 0.79 | HTR1A (0.58) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL4558892 | 0.76 | KDM4E (0.71) | SMN1; SMN2HTR1ADRD2HTR2AMAPT | |
| SCHEMBL6218715 | 0.74 | KDM4E (0.62) | HTR1ADRD2HTR2AMAPTKDM4E | |
| SCHEMBL30890938 | 0.74 | KDM4E (0.62) | HTR1ADRD2HTR2AMAPTKDM4E | |
| Carbamic Acid SCHEMBL28481678 | 0.73 | HTR1A (0.54) | HTR1ADRD2HTR2A | |
| SCHEMBL8469389 | 0.71 | NPC1 (0.37) | NPC1ALDH1A1RAB9ASMN1; SMN2HTR1A | |
| SCHEMBL25287376 | 0.71 | HTR1A (0.41) | RAB9ASMN1; SMN2HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143675-C | Heteroarylpiperidines, pyrrolidines and piprazines and their use as antipsychotics and analgetics | ���µ�˹ҩ�﹫˾ | 2004-03-31 | — | — | CN | disclosed |
| US-5776963-A | ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| CN-1136275-A | Arylheterocyclylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics | HOECHST ROUSSEL PHARMA (US) | 1996-11-20 | — | — | CN | disclosed |