Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711993 | 1.00 | PPARG (0.44) | PPARGPPARASRRALDH1A1CTRB1 | |
| SCHEMBL7232459 | 0.94 | PPARG (0.48) | PPARGPPARACA12CA9LTA4H | |
| SCHEMBL29097240 | 0.86 | CA1 (0.42) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL29097239 | 0.86 | CA1 (0.42) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL15619106 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL5012826 | 0.86 | BLM (0.41) | PPARGPPARAALDH1A1TDP1MAPK1 | |
| SCHEMBL15627203 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL7375987 | 0.86 | BLM (0.41) | PPARGPPARAALDH1A1TDP1MAPK1 | |
| SCHEMBL7344531 | 0.86 | BLM (0.41) | PPARGPPARAALDH1A1TDP1MAPK1 | |
| SCHEMBL2943750 | 0.86 | MEN1 (0.51) | PPARGPPARASRRALDH1A1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836610-A1 | DIGLYCOSYLATED 1,2-DIOLS AS MIMETICS OF SIALYL-LEWIS X AND SIALYL-LEWIS A | Novartis AG (CH) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997001569-A1 | DIGLYCOSYLATED 1,2-DIOLS AS MIMETICS OF SIALYL-LEWIS X AND SIALYL-LEWIS A | NOVARTIS AG (CH) | 1997-01-16 | — | — | WO | disclosed |