Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096114 | 0.87 | MAPK14 (0.57) | GFERHTTMAPK14HDAC1HDAC6 | |
| SCHEMBL7091974 | 0.86 | HTT (0.56) | GFERHTTMAPK14HDAC1HDAC6 | |
| SCHEMBL29336051 | 0.85 | GFER (0.60) | GFERHTTMAPK14HDAC1HDAC6 | |
| SCHEMBL8708978 | 0.83 | GFER (0.67) | GFERHTTMAPK14HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL8715800 | 0.80 | GFER (0.62) | GFERHTTMAPK14HDAC1HDAC6 | |
| SCHEMBL8446728 | 0.79 | MAPK14 (0.68) | GFERHTTMAPK14HDAC1HDAC6 | |
| SCHEMBL8712806 | 0.79 | GFER (0.62) | GFERHTTMAPK14HDAC1HDAC6 | |
| SCHEMBL8710647 | 0.79 | GFER (0.61) | GFERHTTMAPK14HDAC1HDAC6 | |
| SCHEMBL8445235 | 0.78 | GFER (1.00) | GFERHTTMAPK14HDAC1HDAC6 | |
| SCHEMBL8713088 | 0.78 | GFER (0.57) | GFERHTTMAPK14HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998028292-A1 | NOVEL PIPERIDINE CONTAINING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-02 | — | — | WO | disclosed |